Necessary Blood Tests
There are many tests that should be done to test for mold illness/CIRS. Unfortunately, these tests cannot be done with a regular MD, because they honestly don’t even know about them.
So for starters, I recommend finding a naturopath, functional doctor, or a Shoemaker doctor to run the proper tests. If you find a naturopath or a functional doctor you like, make sure they are aware of mold illness or have treated patients with mold illness before, or else they won’t be of much help to you.
Before running any test, you may already be able to tell that you could be suffering from mold illness from symptoms alone. If you have multiple symptoms, maybe 18+ symptoms, you may be looking at mold illness.
The first test you can do is free, and you can do it right from your home. It is called a Visual Contrast Sensitivity Test. You can do it here: https://www.vcstest.com/ . Visual contrast sensitivity testing measures your ability to see details at low contrast levels, and it’s done right from your computer. It will test how capable you are of seeing different imaged in low visual contrast. If you have a hard time with this test, then this is typically a sign that you may be suffering from mold illness. 92% of CIRS patients will fail this test. CIRS patients will often be less capable of seeing the edges of objects/images. This is a reflection of inflammation in the brain. This test can be used to monitor your improvement.
Melanocyte Stimulating Hormone (MSH) — Normal Range 35-81 pg/ml
MSH is typically low in CIRS patients. This test can be done at LabCorp.
Transforming Growth Factor Beta-1 (TGF Beta-1) — Normal Range <2380 pg/ml
TGF Beta-1 is typically high in CIRS patients. High TGF beta-1 will usually cause shortness of breath, and it promotes autoimmunity.
Multiple Antibiotic Resistance Coagulase-Negative Staph (MARCoNS)
MSH deficiency is usually correlated with the presence of MARCoNS. This test should be ordered through Microbiology Dx. This is not a blood test, but rather a swab test in your nose.
C4a — Normal Range 0-2830 ng/ml
C4a is usually high in CIRS patients. This test must be done at Quest in order to get correct results.
Matrix Metallopeptidase 9 (MMP-9) — Normal Range 85-332 ng/ml
MMP-9 is typically high in CIRS patients. This test can be done at LabCorp. MMP-9 is released in the body in response to inflammatory chemicals produced by your immune system.
Vasoactive Intestinal Peptide (VIP) — Normal Range 23-63 pg/ml
VIP is typically low in CIRS patients. Symptoms of low VIP is typically shortness of breath with exertion. Therefore, exercise may be difficult due to low oxygen levels.
Dysregulated ADH/Osmolality levels occur in about 80% of CIRS patients.
Antigliadin Antibodies (AGA) — Normal Range 0-19
High AGA results will show an inflammatory response to gluten. About 33% of CIRS patients have high AGA. This person will usually conduct electricity, and therefore may experience static shocks.
Vascular Endothelial Growth Factor (VEGF) — Normal Range 31-86 pg/ml
Early on in CIRS, there can be an increase in VEGF as your body is trying to compensate for low oxygen delivery. But VEGF can be high or low. If VEGF is high, then this is an indication that your body is trying to compensate for low oxygen levels. If VEGF is low, this is an indicated of reduced oxygenation.
This is a genetic test for mold sensitivity. If you’re wondering why some people become chronically ill from mold, and others recover quickly or have no symptoms at all, then this gene will tell you why. Approximately 24% of the population have the genetic predisposition to be affected by mold. I believe this is one of the most important tests to have done.
This is another genetic test used to detect two relatively common mutations in the MTHFR gene that are associated with elevated levels of homocysteine. MTHFR mutations affect your body’s ability to detox, so it is very important to know.
Mycotoxin Urine Tests
Usually a Shoemaker doctor will not order this but a naturopath/functional doctor will. These can be used to assess people who suspect mold illness.
MRI with NeuroQuant
A NeuroQuant is an software used to accurately measure the volume of different parts of your brain. Some parts are you usually enlarged, and other parts of the brain usually shrink. CIRS patients from mold usually will have an increase in the forebrain, cortical gray, hippocampus, and pallidum. And they will usually have a decrease in caudate.